ABSTRACT
Background: Demonstration of safety is very significant with COVID-19 vaccines, not only for vaccine acceptance but also for trust in vaccination broadly. Therefore, it is crucial to understand various mistrusts regarding COVID-19 vaccine. The aim of the study was to investigate the knowledge and attitude regarding COVID-19 vaccine and its self-reported adverse effects among staffs and students of dental college in Himachal Pradesh. Materials and Methods: This was a descriptive, cross-sectional study conducted among the students and staff members of H. P. Government Dental College and Hospital, Shimla, Himachal Pradesh. All those who received the vaccine from January 22 to February 8, 2021, were included. The survey was divided into two sections. Section 1 of the questionnaire included 14 questions which were regarding the knowledge and attitude of COVID-19 vaccine, whereas Section 2 of the questionnaire included a table with 13 symptoms, and the participants were asked to check the postvaccine symptoms whichever they experienced with the duration. Results: Majority, i.e., 94 of the recipients had pain at the injection site which had a duration range of 24 h to 4-5 days. Of 111 participants, 88 had a symptom of chills lasting 8 h to 48-72 h. 74.5% were hesitant to treat patients due to COVID-19 infection worries. 75.4% considered the need to follow COVID-19 appropriate behaviors such as wearing mask, maintain social distancing, and not going to crowded places even after vaccination. Conclusion: Participants in this survey reported favorable attitudes toward vaccination. The commonly reported adverse effects of vaccination were pain at injection, chills, body ache, and fever.
ABSTRACT
Introduction: Ocular complications in critically ill patients is common. Up to 42% of intensive care unit patients can have signs of damage to the corneal surface of the eye (exposure keratopathy), which can lead to secondary complications and ultimately irreversible visual loss1,2 (Rosenberg and Eisen, 2008;Bird et al, 2017). Emergence of COVID-19 pandemic has meant increased number of critical care admission with inherent risk of ocular complication owing to need for non-invasive ventilation, mechanical ventilation and prone ventilation. All these factors have resurfaced need for increased awareness and adherence to national standards related to eye care in critical care3 (Royal college of Ophthalmology and Intensive Care Society joint Ophthalmic service guidance). Objectives: To study baseline knowledge and awareness of eye care practices in neuro critical care unit. To measure compliance of national eye care guidance. Methods: Structured online survey for critical care nurses. Review of hospital IT software to study snapshot of eye care compliance. Results: We ran baseline survey of neuro critical care nurses on knowledge and current practice of eye care in ICU. Eye care complications in ICU are common with 1 in 5 individual reporting > 3 ocular complications in last 3 months. Three-quarter of individuals reported to have good to very good knowledge of eye care protocol with 66% aware of current national guidance. 86% of respondents assessed lagophthalmos while 76% assessed conjunctiva and cornea routinely. On the flipside however only 60% routinely documented eye care measures in clinical practice. Importantly, 96% responded that they would benefit from education and training in eye care practices. Review of hospital records for eye care compliance and documentation validated the findings on the survey. We found 68% compliance rate for assessment of lagophthalmos in all admitted patient in neuro critical care unit. There was 100% compliance to institution of protective measures and appropriate escalation to medical staff. Graph 1: Baseline survey of knowledge and practice of Eye care in Neuro Critical Care Unit depicting a stepladder pattern in knowledge, practice and documentation of Eye care. Conclusion: Knowledge and awareness of eye care practices fall below national guidance. There is clear gap in knowledge, practice and documentation of eye care practices. Incorporation of eye care module in continuous training program and use of cognitive aids may help to further improve compliance and documentation of eye care practice in future.
ABSTRACT
The outbreak of the COVID-19, a human beta coronavirus severe acute respiratory syndrome (SARS-CoV-2) virus infection, has severely affected the world. The pandemic is not yet in full control due to a lack of rapid diagnostics and therapeutics. This viral infection continues to result in a steadily increasing loss of life, and it has also emerged as a significant global socio-economic burden. As result, it has united many countries for the purposes of exploring molecular biology, biomedical science, and the nanotechnology to manage COVID-19 successfully. As of today, the current priority is to investigate novel therapies of high efficacy and smart diagnostics tools for early-stage disease diagnostics along with monitoring. Keeping these advancement and challenges in mind, this perspective article mainly highlights the contribution and possibilities of bio-nanotechnology to manage the COVID-19 pandemic, even in a personalized manner. Authors also pinpoint barriers to the utilization of current bio-nanotechnology to facilitate a more accurate understanding of COVID-19 and to lead the way toward personalized health and wellness. Furthermore, we follow the discussion of the features and challenges in upcoming bio-nanotechnology approaches for COVID-19 management. In this progressive option report, bio-nanotechnologies that have been enriched with the power of artificial intelligence and optimized at the personalized level have been found to lead to a sustainable treatment and cure strategy at a global population scale. Copyright © 2020 Paliwal, Sargolzaei, Bhardwaj, Bhardwaj, Dixit and Kaushik.
ABSTRACT
Background The authors present an unusual, unreported oral adverse effect of COVID-19 vaccine as palatal petechiae lesions. Case presentation COVID-19 disease caused by severe acute respiratory syndrome coronavirus 2 has become a global health crisis and has caused millions of deaths worldwide. Vaccination programs have been initiated in many countries for COVID-19 prevention. The ChAdOx-nCoV-19 vaccine has been shown to provide a robust immune response in various clinical trials. It is well tolerated by recipients and has been associated with minor adverse effects. The COVISHIELD (ChAdOx-nCoV-19) vaccine developed by AstraZeneca/Oxford University is approved by the Government of India to be administered in a phased manner. We present the case of twin subjects who suffered various adverse effects after receiving the COVISHIELD vaccine;one of the twins presented with palatal petechiae lesions presumably caused by the vaccine. The lesions were self-limiting and required no treatment. Conclusion Oral lesions reported first time in our case should be correlated with similar lesions found post-COVID vaccines globally. There is a further need to ascertain a high level of scientific evidence and explore the biological plausibility underlying oral complications and COVID vaccinations.